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Cholerny Spammer
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 Posted: Thu 1:09, 17 Mar 2011 Post subject: uggs nederland Three cases of collapsing glomerulo |
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Collapsing glomerulopathy clinical and pathological report of three cases
Segmental glomerular capillary wall shrinkage, fold, collapse. Fluorescence mostly negative or small number of patients showed a le, M, weakly positive. In addition to changes in light microscopy electron microscopy is still visible outside the reticular nucleus of visceral epithelial, mesangial area and glomerular capillary wall electron-dense material seen. Similar to the change in foreign reports l2.3J. Third, the clinical features of three cases of CC in this group 2 cases with nephrotic syndrome range proteinuria or nephrotic syndrome, hypertension, renal function deteriorated rapidly, 1 patients with mild proteinuria, the lesions are relatively mild, 2 patients 6 months developed chronic renal insufficiency (1 case of end-stage renal failure), suggesting that the majority of disease progression in patients with rapid cG, prognosis is poor, this observation similar to foreign reports L. Fourth, diagnosis and differential diagnosis of nephrotic syndrome patients and the range proteinuria in patients with nephrotic syndrome, should seriously be recognized according to CG features, its in the short term deterioration of renal function of the FSC, S CG patients should expect the possibility of according to their light and electron microscopy features of pathological changes in diagnosis can be made. Foreign reports H1V patients with renal pathological changes similar to the CC [2,[link widoczny dla zalogowanych],3,7 J, but the H1V-AV patients,[link widoczny dla zalogowanych], glomerular endothelial cells in the electron microscope more than a pipe network including physical, blood, and H Ⅳ HIV antibody positive, with HIV and easy sense of other performance factors and HIV, this paper three cases of HIV-negative CC patients, nor the performance of the other can be ruled out. Fabry disease, although a visceral epithelial cell hypertrophy, vacuolation,[link widoczny dla zalogowanych], but the electron microscope a large number of epithelial cells in park-like concentric osmiophilic bodies, can identify with the CC. V. pathogenesis is not clear. A large number of studies confirm previous glomerular epithelial cells (visceral epithelial cells, the same below) in the body can not regenerate under normal, replication, any damage or loss caused its no substitute for or replace other cells L. CG pathological changes observed in glomerular epithelial cell hypertrophy, hyperplasia, and sometimes showed a multi-core, has aroused great interest and importance, and has many of its pathogenesis reported. Scray such as proliferating cell nuclear antigen PcNA J found that the patients in the cG expression of mesangial cell nuclei positive rate, Themas, etc. 【J that the CG glomerular vimentin and PcNA increase,[link widoczny dla zalogowanych], Y. Yang and other LBj epithelial cells found in CG patients have abnormal expression of WT1 and Pax-2 protein. The exact pathogenesis of CC-depth studies need to be further short,[link widoczny dla zalogowanych], CC is the existence of certain specific pathological changes, clinical manifestations, often more serious and often poor prognosis subtype of FSGS, it is worth attention.
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