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Propofol and midazolam domestic forces for the clinical observation of gastroscopy


Journal 2004, Volume 16 No. 5 Table 1 induction and recovery time memory loss, respiratory depression, sense of self, I, Ⅲ and Ⅱ group of 215 groups difference was significant (P 0.05). No memory of Endoscopic examination 26 patients were I, Ⅱ, 16 cases, Ⅲ group of 29 cases. Rate of respiratory depression, I 2 with breathing pauses, 3 cases of group 3 patients had glossocoma will hold their jaw,[link widoczny dla zalogowanych], we can maintain normal SPO2; feel I, Ⅲ two groups after checking all the patients is very clear satisfaction. Table 23, changes in vital signs Note: I group than in the same. P 0.05). Essential to maintain normal MAP group Ⅱ. HR 3 patients the same trend, 1min after injection, slightly increase or no change, while in the home showed a transient mirror faster, the difference between groups was not significant (P> 0.05). SPO2 change I group, 5 cases 1 ~ 3min after injection, decreased to 93% below its lower jaw can hold up without special treatment. SPO2 change Ⅱ, Ⅲ were normal in both groups. 3 for a discussion of domestic forces Propofol intravenous anesthetics, the role of fast, short duration,[link widoczny dla zalogowanych], recovery rapid, adverse reactions. Propofol force on the circulatory and respiratory functions have a certain impact. I observed in this study group of patients in 1 ~ 3min after the injection pressure drop, and the longer the preoperative fasting, age was negatively correlated with arterial blood pressure more evident. Heuss, etc.] that allow peripheral expansion and propofol on myocardial suppression; reasons for the decline of blood pressure also increased the dose of propofol, opioids preoperatively and antipsychotic drugs, low blood volume,[link widoczny dla zalogowanych], decreased sympathetic tone and elderly and so on. The data also found that patients can force Propofol shallow breathing, slow down, or even apnea, SPO2 consequent decline, for the large decrease in the duration or longer, and those who glossocoma who hold up the jaw to give, more energy rapid recovery. Midazolam is a water-soluble, short half-life of the benzodiazepine drugs, its rapid onset, minimal impact on the normal cardiovascular system, has some inhibitory effect on respiration, the degree of dose-related. Low-dose (intravenous O.075m ~ kg) did not affect the ventilatory response to CO2, so the safety factor and has the better role of sedation and amnesia. In this study,[link widoczny dla zalogowanych], patients were observed after treatment in group Ⅱ MAP, HR, SPO2 basically stable,[link widoczny dla zalogowanych], but the sedation grade, recovery time, memory loss, sense of self, was not as good as I, Ⅲ groups that force Propofol inhibited more stress than midazolam response, increasing the patient's tolerance. We use a small amount of intravenous midazolam in advance can significantly reduce the power of Propofol sedation requirements, thereby reducing blood pressure, the incidence of respiratory depression. Although some patients in the combined treatment group 1 ~ 3min after the injection decreased arterial blood pressure greater than 15%, but most of 3min or so back to normal, compared with the pure power of either Propofol blood pressure, or blood oxygen saturation changes were relatively stable . We believe that co-force Propofol and midazolam, both can use the power of Propofol induction and rapid recovery advantages and midazolam for sedation, anxiety characteristics, and also avoid the relative induced with midazolam alone recovered slowly, the characteristics of intraoperative discomfort .