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Cholerny Spammer
Joined: 03 Mar 2011
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Location: England
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Posted: Thu 9:31, 17 Mar 2011 Post subject: UGG boots Italia wpx jmf frf kap |
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,[link widoczny dla zalogowanych]
Intrathecal and intracerebroventricular injection of mibefradil chronic sciatic nerve loose ligation of the pain threshold of rats
Inhibition of pulmonary artery and right ventricle uT expression. Keywords : puerarin ; urotensin Ⅱ; receptor ; chronic hypoxia ; pulmonary hypertension of chronic hypoxic pulmonary hypertension in chronic obstructive pulmonary disease to the development of key aspects of pulmonary heart disease , its pathogenesis is very complex, ,[link widoczny dla zalogowanych], Abnormal vasoactive substances play an important role. Urotensin Theeffect0fmibefradiladministeredintrathecallyandlateralventricletothepainthresholdoftheratsfollowingchronicconstrictioninjury (CCI0fthesciaticnerveCHENZhi-xin, WENXian-jie, ZENGYin-ming, FANGZhi-yuan (1.DeptofAnesthesiology, FirstAJ ~ liatedHospital,[link widoczny dla zalogowanych], ChinaMedicalUniversity, Shenyang110001, China; 2.JiangsuInstituteofAnesthesiologyandtheKeyAnesthesiaLab, XuzhouMedicalCollege, Xuzhou221002, China; 3.DeptofAnesthesiology, theMunicipalHospital , Suzhou215002,[link widoczny dla zalogowanych], China) Abstract: AimToinvestigatetheroleofTtypecalci-amchannelofspinalcordandsupraspinalonthepainthretholdoftheratsfollowingchronicconstrictioninju-ry (CCI) ofthesciaticnerve.MethodsIntrathecalandlateralventricleinjectionwereemployedinthisstudy.WithVonFreyhairandradiantthermalstimula-tor, wemeasuredthemechanicalwithdrawalthreshold (MWT) andthermalwithdrawallatency (L) oftheratsafterinjectedmibefradil.ResultsTheratsofCCIgroupformedsteadymechanicalandheathyperaglsiafromthethirddayafteroperationtotheendofthisstudy.Administeredintrathecallymibefradil50,[link widoczny dla zalogowanych], 100,200 gcanincreasetheCCIratsMWTandrWL.However, mibefradiladministeredlateralventriclecanreducetheCCIratsMandTWL.ConclusionBlockingTtypecalciumchannelofspinalcaninhibitmechanicalandheathyperalgesiaoftheCCIrats, However, blokingtheTtypecalciumchannelofsu -PraspinaleaRenhancethemechanicalandheathyper-algesiaoftheCCIrats.Keywords: spinalcord; supraspinal; neuropathicpain; Ttypecalciumchannel; painthresholdmeasured
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