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Posted: Mon 12:59, 07 Mar 2011 Post subject: true religion 美多巴ງ |
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美多巴配合运动疗法提高运动干预脑梗死患者肢体功能的对照观察
ceandabnormalmusculartoneandthehospitali~ationcoIl鹏weresignificantlyshortenedinMGheat加Ientgroup【(36±11)ht上l(55±20)h,(34±18)ht上l(5O±19)h,[link widoczny dla zalogowanych],(252±37)h∞(280±50)h,P<0.05】.Level8ofprolnflam.matorycytokinesinthesupernatantofPBMCafarrv1GUeatmentweremuchlow盱thanthosebdomIⅥGtreatment【0frrNF-Q(1.0±1.6)/L侣(4.2±3./I’ofⅡ,1p(1.1±1.5)几∞(3.4±3./I’ofII,6(O.8±1.4)Lg/Lw(3.0±3.2)Lg/P<0.011.ThereWeA'~in.significantdifferencesinroutinegroupbeforeandafterUeatments.Con-dusionMGhascurativeeffectsonconsciousnessdisturbanceandab-normalmusculartoneinHIEinadditiontoconventionalUeatmentreg.衄en8,whichisassociatedwithinhibitionoftheproductionofIla'OilfflammatolWCy.tokinesbyPBMC.taCTHEADINGS:cerebralanoxia;cembratischemia4immunoglobuliusintraveneous,[link widoczny dla zalogowanych];intexleukina;tumornecrosisfactor摘要:目的探讨静脉注射免疫球蛋白(IVlG)改善新生儿缺氯缺血性脑病(HIE)患者意识、肌张力摩碍的临床疗效及其作用机制。方法将4o例HIE患儿随机分为MG治疗组及常规治疗组。比较两组患儿临床症状、体征消失及住院时间;并采用ELISA法检测患儿治疗前后外周血单个棱细胞(PBMC)产生肿瘤坏死因子一Ⅱ(TNF.Ⅱ)、白细胞介素一1B(IL一1B)和白细胞介素一6(IL-6)的水平。结果与常规治疗组相比,IVlG治疗组患儿意识、肌张力摩碍等症状消退时间及住院时间较常规治疗组均显著缩短【(36±I1)h∞(55±2O)h,(34±1h∞(50±19)h,(252±37)htH(280±50)h,t=2.04~3.63。P<0.05】,[link widoczny dla zalogowanych]。rv1G治疗后患儿PBMc产生前炎症细胞因子水平明显低于治疗前【TNF.Ⅱ:(1.0±1.6)g/LtH(4.2±3.g/L,Ⅱ,1p:(1.1±1.5)g/LtH(3.4±3.g/L,Ⅱ,6:(0.8±1.4)g/LtH(3.0±3.2)g/L,P<0.01】,而常规治疗前后无明显差异。结论IVIG早期应用对改善HIE患儿意识、肌张力摩碍具有较好疗效,可能是通过抑制PBMC产生TNF-ot,Ⅱ,1B和Ⅱ,[link widoczny dla zalogowanych],6等损伤性细胞因子发挥作用。主量词:脑缺氧,[link widoczny dla zalogowanych];脑缺血;免疫球蛋白类,静脉内;白细胞介素类;肿瘤坏死因子0引育近年来研究表明,免疫细胞因子在中枢神经系统多种生理、
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