Forum pracy nad projektem wskrzeszenia The Forge

[yoylqnqvwb]

Mycobacterium vaccae vaccine adjuvant treatment of tuberculous exudative pleurisy of clinical observation


) Per selection criteria: (1) clinically diagnosed as TEP, chest X-ray taken on clinical examination, or B-; (3) monthly blood test, urine and liver x-ray examination, pleural fluid tests, ECR and other groups in the incidence of hospital within two weeks of renal function; (4) observation M. vaccae toxicity. Patients. (2) Age 20 to 70 years of age. (3) no serious heart, liver, 1.4, determine the effect of diabetes and kidney disease. (4) allergic diseases without immunity. Recent therapeutic efficacy by 1.4.1: Press Conference of 1982 marked the national structure of the standard disease patients 5O TEP selected cases, 35 cases of men and 15 women associate. Cure: pleural effusion completely absorbed, without pleural thickening. Markedly: chest cases,[link widoczny dla zalogowanych], mean age 50 years, by sex, age, lesion, pleural effusion completely absorbed, and the remaining mild pleural thickening (limited to the costophrenic angle). A comparable amount of fluid matched randomly divided into treatment groups: chemotherapy Aspiration efficiency: pleural fluid absorption, left pleural thickening more pronounced (up to the diaphragm dome or + M.vaccae ~ control group: chemotherapy + pumping fluid + hormones. More) . Invalid: the end of treatment still pleural effusion. Worse: pleural effusion still 1.2, treatment programs and / or pulmonary tuberculosis there. Treatment: 6 were treated (2 topical, systemic 1.4.2 determine the long-term effect: the two groups after treatment, respectively,[link widoczny dla zalogowanych], in section 3,6, medication 4 times), or pumping the chest after the direct injection liquid 22. 5ug, week,[link widoczny dla zalogowanych], months after the follow-up 12,24. Photo by chest X-ray and / or B-mode ultrasound view by pumping a liquid and then note the same dose. The second weekend from chemotherapy, 2 years after stopping effect observed. Invalid: There is residual pleural effusion and / or encapsulated deep intramuscular injection once every four weeks,[link widoczny dla zalogowanych], each dose 22.5ug. Effusion. Relapse: recurrence of pleural effusion asked two years and / or chemotherapy in lung appears Results: Treatment group: 2HRZE/2HR. Control group: nuclear lesions. Both of the above collectively referred to as treatment failure. 2HRZE/4HR. Aspiration in the same way the two groups, using the results of continuous pumping liquid to 2 pleural effusion completely disappeared. Hormone therapy is oral prednisone daily 2.1 determine the efficacy of 30mg, decreasing the amount (5 to 7 days reduction 5rag) to stop comparing the total course of treatment 2.1.1 (see Table 1) 4-6 weeks .... Author: Zhaoqing City, Zhaoqing, Guangdong 526020 TB Zhaoqing the school No. 1 in 2004 (total 49) Table 1M. vacca treatment group compared with the effect of hormone control group 2M. vaccae treatment of pleural effusion group and the control group the average hormone l mean absorption time I sucked the treatment group than the control group by M. vaccae adjuvant therapy, TEP shortened two months of chemotherapy treatment 2.2M. vaccae vaccine side effects: adverse reactions and the light,[link widoczny dla zalogowanych], by the way (the actual average time of 4.3 months of chemotherapy) symptomatic treatment can be lost, with no severe allergic reactions and no shock, hepatic hydrothorax 2.1.2 mean absorption time compared (Table 2) renal dysfunction and other systemic side effects. 2.3 years follow-up results (Table 3) Table 3 treatment group and control group 3 years follow-up discussion of the results of Mycobacterium vaccae (M.vaccae) vaccine (trade name Micro Card vaccine) is in the 9O's wHo The only recommended dose of tuberculosis immunization, micro-card vaccine (from Anhui Dragon Coma biopharmaceutical limited liability company) by Mycobacterium vaccae vaccine made of purified inactivated at high temperature immunomodulator on the immune dysfunction host a stimulating effect, enhance immunity, on the immune status of hyperthyroidism in the ultra-sensitive from the host's immune system is suppressed or reduced effect. When TB and its metabolites into the body of M. tuberculosis allergic pleural cavity, can cause TEP. In the systemic chemotherapy, based on the M. vaccae intrathoracic injection of small doses, can regulate the body hypersensitivity, inhibit or reduce the generation or exudative pleural effusion, can be activated in the pleural cavity and pleural lesions of tuberculosis, to help chemotherapy to kill. The traditional view that glucocorticoids on l6 · prevent pleural adhesions, pleural fluid absorption to promote a positive role, but also some side effects may occur, they can still cause TB spread. ... This is the prevention and treatment of TB in contradiction. Clinical observations indicate that M. vaccae adjuvant treatment of hormone adjuvant therapy can be used instead to avoid the use of hormones during the course of immune suppression and other side effects, can improve immune function, enhance the efficacy of chemotherapy, reduce the chemotherapy treatment, reducing recurrence of TEP, is worthy of clinical use.