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Norvasc treatment of essential hypertension


. Serious heart, liver, kidney damage and other than the drug had Minken. Selected in 6 cases before the use of antihypertensive medication. However, blood pressure control is not ideal. 1.2 Methods: Norvasc single drug itself before and after treatment were observed. 6 weeks. Including 2-week observation period and 4 weeks treatment period. Disable all patients before treatment other antihypertensive drugs for 2 weeks. Deletion of the right arm before treatment seat nIL pressure of 3 times. The mean value. As a treatment based on blood pressure,[link widoczny dla zalogowanych], diastolic blood pressure should be 11.97kPa,[link widoczny dla zalogowanych], increase the dose to lOmg / d = down 8 patients in the course of four weeks and treatment of the end of the last week of observation,[link widoczny dla zalogowanych], respectively, once a 24-hour ambulatory blood pressure monitoring. 1.3 Clinical criteria: the treatment of blood pressure compared with baseline blood pressure before treatment m | Binh Dinh antihypertensive effect. Cardiovascular epidemiology reference 1979 meeting standards. (1) markedly effective: diastolic blood pressure to normal range and the decrease of ≥ 1.33kPa; or diastolic blood pressure to normal + but the magnitude is not ≥ 276kPa (2) effective; DBP o. 67-12kPa, and dropped to normal range: or diastolic blood pressure were not reduced to normal,[link widoczny dla zalogowanych], but the decline ll332.53kPa. Or systolic blood pressure decrease ≥ 4Kpa (3) ineffective: less than the effective standards. 1.4 Statistical Methods: The results of measurement data to mean ± standard deviation (X),[link widoczny dla zalogowanych], said: line t test. 2 Results 46 patients with hypertension taking Norvasc blood pressure began to decrease after the first week. Stable blood pressure four weeks. Blood pressure after treatment than before treatment were significantly different (P <random 01), the total effective rate was 913 (42/46), 8 Ba line 2 {-hour ambulatory blood pressure monitoring of patients, 6 had served public funds in the live hi 5mg / d. 2 cases of Service Norvasc tOmg / d + mL cure before the 24-hour average pressure 1901kPa/1223kPa, 24 hours after treatment, average blood pressure 16.6211.03kPa. There was a significant difference (P <0.01). 46 down around 8 pm in patients with eye drops every morning + at this time for the low serum concentration time before and after treatment according to the + mean change in blood pressure values ​​before and after treatment and 24-hour mean blood pressure change in the maximum value of (2:00 pm). Calculation of systolic and diastolic blood thirty A peak ratio of the peak rate + systolic blood pressure (P value) (2: oo) is 3.14kPa, trough (T value) (8: OOam) 2. t2kPa. The ratio of the peak P value of diastolic blood pressure was 67.8 (2:00 pm) as 223kpa. T is 1. ? 3kPa. The peak ratio was 8. j7, shows Norvasc stability control in the 24-hour blood pressure 3 Discussion Norvasc is a long-acting dihydropyridine calcium antagonist pair in the selective expansion of the role of the small arteries half-life of up to 3550 hours, blood with peak drug concentration of 6-12 hours. Fixed this. Stable antihypertensive effect. Lasting. Maintain more than 46 back in 24 hours with primary hypertension treatment Norvasc. Effective in 42 cases. Which markedly in 37 cases, total effective rate of hypertension was 91.3 per day in patients taking 5rag 38 cases. Taking lOmg of 9; that the antihypertensive effect of the drug a day trip is good. The short-acting calcium antagonist from the F fast onset. Short duration of action. General medication can not control the way after midnight and early morning blood pressure. So we take short-acting antihypertensive drugs. Increased blood pressure is still dominated and volatile morning in patients treated with Norvasc, a satisfactory antihypertensive effect. And mild adverse reactions. 2 cases of headache, 1 case of lung floating ankle, no withdrawal, headache gradually reduced. Norvasc treatment of essential hypertension has obvious advantages. Only once a day medication, stable blood pressure for 24 hours. Avoid drastic changes in blood concentration, blood vessels caused by the rapid expansion of some adverse reactions; the same time. The reduction of target organ damage. Reduction occurred at night and the morning of sudden cardiac vascular lesions of rodents is also important. Therefore, Norvasc is the treatment of essential hypertension an effective, safe, reliable, convenient drug for long term use. (Presiding Editorial: 19,990,402 wearing military leave weep draft)