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Prevention of amiodarone without Magnesium acute myocardial infarction percutaneous coronary intervention reperfusion arrhythmia


inger method line about coronary angiography. Occlusion or near occlusion before stent implantation in 246 amiodarone without Magnesium prevention of acute myocardial infarction percutaneous coronary intervention reperfusion arrhythmias full balloon dilation. None of the patients with distal protection devices. Intraoperative heparin given 100IU/kg. 1.4 statistical software statistical analysis using SPSS10.0, count data expressed as a percentage, the line x test, measurement data as mean ± standard deviation (± s),[link widoczny dla zalogowanych], said group data by t test. To P 0.05). 2.2 A group of reperfusion arrhythmias occurred in 11 cases of reperfusion arrhythmias, including ventricular premature beats in 6 cases,[link widoczny dla zalogowanych], 3 cases of acceleration of spontaneous cardiac rhythm,[link widoczny dla zalogowanych], sinus bradycardia in 2 cases; B group of reperfusion arrhythmias occurred in 20 cases, including eight cases of premature ventricular contractions, accelerated ventricular rhythm independently in 3 cases, paroxysmal ventricular tachycardia in 5 cases,[link widoczny dla zalogowanych], 2 cases of sinus bradycardia, II degree AV block two cases, A group than in group B low incidence of reperfusion arrhythmias (12.9% V824.7%, P <0.05). A group 1 patients had QT interval prolongation to the 0.6s and disabled during the operation of amiodarone, all of the other patients to intravenous amiodarone after 8h, no significant side effects. 3 Discussion AMI recanalization and reperfusion arrhythmia calcium overload and oxygen free radicals are closely related to two main factors. Amiodarone can increase the stability of electricity; dilation of blood vessels; no negative inotropic effect; induced arrhythmia is very low. Potassium-magnesium aspartate to aspartate and potassium and magnesium aspartate mixture. Aspartate is a high degree of affinity with the cells of amino acids, potassium and magnesium as a carrier to easily enter cells and improve the concentration of intracellular potassium and magnesium, magnesium ion is a Na a K ATP necessary to activate the enzyme factor, can maintain the permeability of ions inside and outside cells, while Mg It has been reported for 60% of reperfusion arrhythmias and early afterdepolarization about j, and magnesium ions to cells when the repolarization phase in 4 sodium, potassium, calcium, respectively, the concentration of low-gradient from the pump back to the high gradient in situ to go back to normal polarization state j. 8h after taking into account the PCI I have completed full reconstruction of the blood away, 8h less the case outside the arrhythmia, it is designed to continue after 8h of treatment programs. Emergency PCI in this study, the application of preoperative prophylactic agent in patients with amiodarone and magnesium after the occurrence of reperfusion arrhythmias was significantly reduced compared with the control group (P <0.05). Preoperative amiodarone in patients with only 1 patient had QT interval prolongation, and no other obvious side effects, indicating that prophylactic preoperative vein is relatively safe. However, clinical application, or should be very cautious and pay attention to individual differences in intravenous drug should be monitored during the patient's electrocardiogram, blood pressure, prevent a transient hypotension, QT interval prolongation and other possible adverse reactions.