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Pulmonary fibrosis in rat plasma MIP-1α, MCP-1 levels in the observation of dynamic changes


systemicselemsls: MCP-1andMIP-1dmaybeinvolvedinthedevelopmentofpulmonaryfibrosisCfinExplmmunol, 1999, I17 (1): 1596GharaeeKMtphenSh. Theroleofeo ~ inophilsinpulmonaryfibmsis. IntJM0 【Med, 1998.1 (1): 45 (2001-04-11 2001-07-28 receive your samples they enjoy the back) 1slnjthRE. StneterRM. PhansH. Pr. Tu jo Ⅱ du pan dfuncn. f (Feng text editor thing holding) murinemaemphageinflammatoryprotein a 1Qinbleomyc ~ n-in-· short match reports plateau retrograde venous treatment of skin avulsion Efficacy 850,003 Remington Lhasa Tibet Military General Hospital, Lei Jing Xin all related anxiety feeding arteriovenous anastomosis ■ ; planing injuries and injury-book materials in China Tian DOI R641 35 patients, 26 males and 9 females, down; age of L2 ~ 48 years, mean 28.6 years old. 6 ~ 48h after injury, one hospital. 35 cases, 32 fell more complete avulsion of the skin. Network of veins remains continuous, extensive skin contusion, avulsion area lOcm × 7 ∞ ~ 23cm × 26cm sections washed repeatedly washed with saline, and plated with a 1:1000 benzalkonium bromide (benzalkonium bromide) soaking the wound profile from shallow to Yao Hang the end of the Qing plane, hit by pollution and loss in addition to all living tissue. Clear profile in the inner surface of the skin when the avulsion attention as much as possible within the protective subcutaneous fat layer of superficial vein, and the ends to protect the well marked to facilitate the match during the event. Ministry of tissue damage associated with Yao, should first fracture reduction and fixation, while the tendon, blood vessels and nerves. Avulsion of the skin and then reset, under the microscope with the suture needle without injury 1l0 subcutaneous superficial vein anastomosis, vein diameter of 0.4 ~ 2.6ram at least match 2, match up to section 6 placed under the wound suture drainage strip, limb fixed in plaster work with Vladimir bit, after conventional antibiotics, antispasmodic treatment for 3 to 5 days were 32 down 35 down the wound a bird together. Survived completely avulsed skin, wound care rate 91.4 disk 3 patients had partial necrosis of the skin, which I love cover down the line profile of free skin grafting, 2 dressing down by the local highland areas of skin wound healing in the treatment of retrograde features of avulsion injuries: lack of the alpine plateau of chlorine, chlorine causes low body hyperlipidemia, blood kwu thick, slow flowing chlorine and the lack of compensatory increase in capillaries, causing tissue generates too much possession, resulting in local tissue swelling, and further increase the emblem of circulatory disturbance, therefore, in the plateau region to simply reverse avulsion of the skin sutured drop-easily lead to skin necrosis with avulsion consistent with retrograde venous treatment of skin avulsion, good effect may be due to retrograde skin avulsion of superficial venous anastomosis, the skin blood get back to the pool, chlorine for maintaining the skin and nutrition, combined with the lotus gradually wound between the skin and plate together to establish a profile of collateral circulation, avulsion of the skin can be restored physiological blood supply. Another report, the skin is a low chlorine organs, including the minimum to maintain the skin into the chlorine partial pressure 6.65kPa, only after the blood flow through the tissue metabolism of about 3O% chlorine was used, and venous partial pressure of chlorine is still within the There 10.03kPa, so the blood is able to maintain a simple existence, including the result of skin, superficial venous anastomosis alone can ensure the skin avulsion profile retrograde blood supply to the skin as included to provide a reliable guarantee. Clear profile of high altitude plane wound time limit: the plateau region due to long hours of sunshine, UV intensity, climate, Han Ling, dry and not conducive to bacterial growth and reproduction. Experimental studies confirmed that the Tibetan Lhasa area of ​​wound infection caused by bacteria standards should be higher than the plain areas, per gram of tissue in the number of bacteria must be in the LO. It had wound infection (I bow from the plain areas of wound infection the amount of bacteria in London 10 per gram standard), and the infection time was longer than the plain areas, the average time frame for the infections caused by 48h. Plain areas within 6h after injury were required debridement, and the Tibetan Plateau can be more than 2O hours late. 24h Feng group were 31 people near the hospital, accounting for 89 of the wound a combined accounted for 91.4% of poultry. This fully shows that the plateau region in the open wounds of the Qing period plane comparable to extend the plain areas, the clear split in the 24h wound closure, no effect on wound healing (2001-02-25 Received 2001-O7-28 they enjoy the back)