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Thymosin treatment of children with foscarnet clinical observation of chronic hepatitis B


2001U / L). A / G ratio <1.8. 6 cases of children with chronic hepatitis B were diagnosed as mild, treatment is not used within six months of interferon, thymosin. Of acute and chronic renal barrier Jiaochu not ill: ① decompensated cirrhosis first {@ heart, renal dysfunction, I @ nervous system diseases} ④ pit had Chong who foscarnet. 1.2 2.4g/100ml foscarnet treatment 150ml diluted with normal saline intravenous 3ht uniform thymosin 40mg / d, plus 10 in 250ml of glucose or intravenous saline. Given simultaneously with foscarnet, 28d 1 ten course of treatment. Treatment Results in Cambodia is not negative when the quantitative HBVDNA sequential therapy can be used. Po 28d withdrawal ① 1.3 standard course of treatment for the 1 +; @ serious adverse reactions, can not stand by; @ deterioration of liver function were 1.4 per item both haunting record of a King 3d symptoms, signs and other conditions change. Each 2W check liver function, routine blood and feces, and serum potassium, calcium, phosphorus, chlorine and 1 King Su feces. Indicators linked to hepatitis B viral Island 1.5 before treatment and after testing HBV. M, again by the Shanghai Branch of China Jing Limited + review by ELISA, wrapped I. HBVDNA by quantitative PCR, Zhongshan Medical University + test Jing An election by the Company. 2.1 * 2 clinical change of station set consolidate the situation before treatment fatigue, anorexia 6 down + distention in 4 cases, medication given node j over Cambodia-like when I have gone hepatosplenomegaly, signs of chronic liver disease after treatment no significant changes in 2 -2 liver Qi to restore the situation in 6 cases in summer (1OO%) ALT were significantly increased (45 ~ 200IU, L) I therapy in 5 (83.3) reverse normalization I1 (16.7%) did not continue oral normal + liver medication to reduce alcohol 6W normalization. Jaundice before treatment and 3 cases (50), TBLI19.5 ~ 4mol / L + treatment were normal (1OO); 3 例 A / G ratio anomaly, did not change significantly after treatment, pain before and after drug treatment 2-3 ho Indexes HBeAg rejection of the situation before treatment in 6 cases (1OO), 4 patients after treatment (66.67) Hu turn, HBVDNA quantitative positive in 6 cases (100), medication at the end of 4 (66.67) Meng turn down positive t1 + HBsAg6 (16.67) 2-4 negative conversion provision of a mince sodium in the treatment before and after the forgotten children HBVDNA quantitative changes in Table 1. 2-5 undercarriage reaction within 1h after treatment in 2 cases mild nausea, the basis of the original number of drops Puritanism on the slow, 10min after the symptoms disappear, continue to apply. 2d wrapped in 1 case the treatment of hepatitis B l6 oblique startled Po treatment of children before and after the startling outcome of quantitative changes HBVDNA loose stools after 2 King, d, by adjusting the diet (hot or cold dish step with) after the application of their own to alleviate the adverse effects over scattered light does not affect the treatment. 3 Discussion 'spleen for the new generation of non-sodium broad-spectrum antiviral glycosides Stubbs, studies have shown that its human cytomegalovirus, EB virus, herpes zoster virus disgrace cancer also inhibit DNA polymerase, while resistance to influenza virus RNA polyol and alcohol immunodeficiency virus reverse transcriptase also inhibit [I] in recent years sodium designated directly inhibit 15I with spleen-specific DNA virus reverse transcriptase poly-alcohols and the role of alcohol, it is widely used in the treatment of chronic hepatitis B + for HBeAg, HBVDNA quantitative conversion rate 66.67 Hu, Meng turn was higher than the natural rate of positive anti-hepatitis B virus effect. Consistent with those reported _1] often in patients with chronic hepatitis has been due to immune dysfunction, immune dysfunction, can not effectively eliminate the virus + cause liver cells continue to replicate HBV in the body t the continuous development of the disease, deterioration of ridicule. Therefore combined immune and antiviral drugs is an important method for the treatment of chronic hepatitis. Combined use of foscarnet treatment of stomach thymus induced T lymphocyte differentiation is mature, enhancing immune function, increased IFN-a, IFN-~, and other lymphatic function due to the formation of [; is conducive to the elimination of the virus. Two drugs act synergistically + is good for patients symptoms disappeared and liver function recovery data showed that drug reactions are mild, children can also be applied + is a safe and effective fast, but promising drugs + Bong turn to teach subjects fell less. To be further explored. Reference ■ 1 Fengshan Cheng Wen Yi Zhang Mu. Jiangsu Chun. Spleen acid treatment of chronic B cricket Park Simuliidae, hepatitis C treatment and education observed small thread - Chinese Journal of Antibiotics, I998.1; 232 fetter the Tao - the progress of antiviral therapy of viral hepatitis drawer. Liver Diseases +1999.1 shame; 1233 Ju Sheng Su, see leaf-dimensional hanging belly enamel. Zhongzhen Yi editor. Park Physiotherapy liver win. 2. Tianjin. Tin Yi of Science and Technology Press, 1993.166