Forum pracy nad projektem wskrzeszenia The Forge

[02fdd68lv]

全反式维甲酸对HL—60细胞hTERT基因表达和端粒酶活性的影响
on“httmalcdIs【JJscience,[link widoczny dla zalogowanych]，1998，279：349～352．9JNAKAYAMAJI，TAIL,klL4HTMtARAEetaI．Telomer,'LseactivationbyhTRTinhttmattrtomullfibrohla_~andhepatocellu]arcarcin0mas【J_,NatGenet，l998,[link widoczny dla zalogowanych]，18：65～68【l0jKONDOS，TANAKAY,[link widoczny dla zalogowanych]，KONDOYetaI．AntisensetdomerasetreaUnent：induction0ftwod3sfinctpathways．apoptosisanddiffcmrtfiation[J一．FASEBJ，l998．12：801～811【1ljXUD,[link widoczny dla zalogowanych]，GRUBERA，BJORKHOI),|M，etalSuppressionoftdomerase1wtranscriptase(hlqERT)expressionindifferentiatedHL一60cells：regulatorymedmnisms[J—BritishJCancer，1999，80：1156～1161．Effectsofall—transretinoicacidonhTERTgeneexpressionandtelomeraseactivityinHL一60cellsHEDong—mei，ZH?d~GYnan(1l~tituteofHertmtology，JNLMC，Guanb-．z]lout510632，China)【AbstractJAim：Toevaluatetheeffectsofall—transretinoicacid(A耵)onhTERTprotein“Pms一$1onandtelomeraseacdvig'inHL一60ceils．Methods：TheexpressionlevelsofhTERTDroteinweIas—sayedbyimmtmofluoreseeneeusingfluoresceisothioeyanate(tree)labe1．Telomeraseaefiviyr、Ⅷdeter—Hunedbypol>xnerasechainreactionen~'rae—linkedimmnnoassay(PCR—ELISA)inHL一60cellsun—treatedortreatedwithA耵．Cellcyclewasanalyzedbyflowe)~ometly．Results：Theexpre5sionlevelsofhTERTproteinweredecreased，telomeraseactivi~,ofHL一60cellsWaSsignificant／vinhibitedwhentreatedthA耵．A．Conclusion：ItissuggestedthatduringthedifferentiationofHIl一60cellsinducedbyATRA,[link widoczny dla zalogowanych]，telomeraseactivityghtbespecificallyinhibitedinHL一60cellsthmL1曲thedo№IafjonofhTERTgeneexpression，anditisfurtherpmvedthathTERTgenehassignificaIltc0rrelad0nwi出telomeraseaefivity．[Keywords]all—trat~retinoicacid；HL一60cells；telomerase；hTERTgene
More articles related to topics：


puma shoes Kiwi Seed Oil physiological role of the

mbt cipo Use of multinational resources to speed u

[link widoczny dla zalogowanych]

[link widoczny dla zalogowanych]

[link widoczny dla zalogowanych]