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Monitoring of hemodynamics and oxygen metabolism in septic shock prognostic value of early


Progress,[link widoczny dla zalogowanych], the mortality remains high n '. Septic shock is caused by infection with abnormal distribution of blood flow as the main characteristics of a shock, manifested as increased cardiac output, peripheral vascular resistance decreased tissue use of oxygen with an oxygen barrier. Decrease in SVRI is one of the characteristics of septic shock and refractory hypotension and SVRI decreased most relevant to a few lines the decrease in cardiac output ¨ '. This performance of CI in most cases by ~ I (60.7%), and SVRI decreased (75%), consistent with early septic shock is characterized by low resistivity high ranked hemodynamic changes. SVRI decreased mainly endogenous inflammatory mediators (such as tumor necrosis factor, interleukin, histamine, etc.) a large number of the release of the extensive expansion of the resistance vessels (5 '. In addition,[link widoczny dla zalogowanych], severe infection, due to vascular endothelial cells injury, reduced the response of catecholamines can lead to a decline in SVRI, which is a consequence of the persistence of high-power state and around the circulatory failure. The study found: CI 70.6% higher than normal mortality group 27.2%, while mortality was higher than the increase in SVRI decreased group, 66.7%. reveal the CI and SVRI may be judged as an early prognostic marker in septic shock. septic shock, CI increase was mainly due to heart rate caused by cardiac oxygen demand inevitably lead to the rapid increase in patients with cardiac perfusion pressure due (MAP) decreased, which means there may be a higher oxygen debt and greater risk of myocardial ischemia. As the toxins and inflammatory factors in 139 * the role of endothelial injury, increased permeability and leakage, shock and abnormal early can have a DO2, DO2 and grouping all of the group there was no significant difference in mortality, suggesting that D02 and V02 Early septic shock is not an ideal prognostic indicator, but as a prognostic indicator 02ER better than DO2 and,[link widoczny dla zalogowanych], 02ER higher and lower group,[link widoczny dla zalogowanych], the total mortality of 81.3%, 16.7% higher than the normal group. normal DO2 and the case showed a linear correlation exists between the district and the supply of oxygen was dependent on platform-like non-linear relationship between the oxygen dependent areas, septic shock, oxygen delivery and oxygen consumption relationship changes. Zhao Liang et al (6 oxygen deficiency proposed, including hypoxia for pathological type, high oxygen consumption type, oxygen uptake and mixed-type disorder. septic shock can be expressed in any type. 02ER often prompted the rise of the relative lack of oxygen supply and oxygen consumption increase in cases of septic shock may be in the early part of the DO2 higher than normal, and often prompts 02ER reduce barriers to oxygen uptake, so the increase and decrease 02ER are poor prognosis. Thus, CI, SVRI, 02ER is early septic shock an important indicator of prognosis in early septic shock should be based on characteristics of hemodynamics and oxygen metabolism to give specific treatment, recycling capacity quickly added to restore hemodynamic stability '; for 02ER prompted the rise of the relative lack of oxygen supply and increase in oxygen consumption patients should maintain adequate cardiac output and oxygen delivery to maintain proper tissue perfusion; for the lower oxygen delivery in patients with normal and 02ER improve the organization should focus on the use of oxygen,[link widoczny dla zalogowanych], thereby enhancing the success rate.
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