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Acute drug poisoning and first aid


Function tests. 2. Convulsions see seizures of patient control, stability and 10mg may be given intravenously, child dose of 0.1-0.3mg, lcg. But pay attention to respiratory depression. Invalid if the stability can be slow to phenytoin l ~ 3mg/kg intravenously. 3. Haloperidol, and decreased muscle tone phenothiazine drugs such as perphenazine, chlorpromazine cloth and sand it piperazine hydrochloride, can reduce acute muscle tension. Adult use of diphenhydramine 10-20mg / times, more than 2 minutes slow intravenous injection. 4. When severe symptoms of paralysis agitans,[link widoczny dla zalogowanych], paralysis agitans anti-drug use, but can enhance anticholinergic toxicity. Benzene Zhatuo optional items (benzatropine) 2mg or Li Teng than piperazine (biperiden) 2mg IV or IM. Symptoms can disappear after the first dose. Maintained after 3 days. Oral dose, benzene Zhatuo goods O. 5 ~ 2mg. 2 times a day, or more than piperazine Li Teng 2mg 3 times a day. These drugs are flushing, dry mouth, blurred vision, nausea, less sweat, individual urinary retention, hallucinations, delirium, withdrawal or reduction after the above symptoms can disappear. Older applications need to consider carefully, if necessary, gradually increase the dose required application. Symptoms of severe anticholinergic toxicity associated with glaucoma were hanged. 5. 1970 Jarvik jaundice jaundice report about 2-4% of patient taking chlorpromazine. Hydrocortisone treatment can be applied, while antibiotics. (D) the application of a specific antidote. Metal complexing agent (1) Ammonia carboxyl complexing agent 1. EDTA calcium indications: Lead and its inorganic compounds, manganese, copper, cobalt, uranium poisoning. Usage and dosage: 0.5 ~ 1. or ~ 0 ~, 5% glucose injection, the intravenous infusion, Qd, 3d as a course of rest between the two treatment 3 ~ 4d. 2. EDTA Indications: digitalis, hypercalcemia, poisonous snake bites. Usage and Dosage: 1g, views, add 40ml of glucose injection, the intravenous, 1 or 2 times, d. Treatment of snake bites, can be 4% to 5% aqueous wash bite site. (2) thiol complexing agent ① two thiol propanol (BAL) Indications: Arsenic and its inorganic compounds, antimony, mercury and gold poisoning. Usage and Dosage: 0.1 ~ 0.2g / times, deep intramuscular injection, poisoning before the 2d, 1 time / 4h, No. 3-6, 1 / 6h, after 1 / 12h, usually with a 7-10d . (B Shu sulfonate indications: arsenic, mercury and its compounds, chromium, gossypol, dimehypo, mushroom poisoning, etc.. Usage and dosage: O.25 ~ 0.5r ~ 0 ~, IM, poisoning before the 2d, 2 ~ 3 times, d, s 3 ~ 7d, 1 ~ 2 times, d, general medicine 7d. 2. methemoglobin anti drug (1) blue (methylene blue) Indications: For nitrite, 22 nitration of benzene compounds, chlordimeform, primaquine morpholine, phenacetin and other drug intoxication caused methemoglobinemia. Usage and dosage: 50 ~ 100mg +20% G.S20 ~ 40ml, intravenous. if cyanosis does not go away, 60min after repeated injection of the original amount of time, as the condition 2 ~ 4h after repeated intravenous injection. (2) vitamin C therapy: the same blue. can be used for the treatment of mild to methemoglobin disease, or as a high re-adjuvant treatment of methemoglobinemia. Usage and dosage: 200 ~ 300mg / ~, 34 times / d, or 2000 ~ 3000rag +10% G.S500ml Ying war drops, 1 or 2 times, d. 3 . cyanide poisoning antidote amyl nitrite, sodium thiosulfate, sodium nitrite. Indications: sodium cyanide, potassium cyanide and its compounds, bitter almond, linseed, cassava and cyanogenic poisonous plants, acrylonitrile and other organic nitrile compounds poisoning. Usage: amyl nitrite 1, placed in gauze after the inhalation of the break, every 2-3rain smoking a until the intravenous sodium nitrite up; 3% sodium nitrite 10 ~ 20ml slow intravenous injection; 25% sodium thiosulfate solution,[link widoczny dla zalogowanych], 50ml, slow intravenous injection, if necessary, repeated injection of half dose after 1h or full volume. 4. opioid poisoning antidote. naloxone (that Nuosong) Indications: morphine, opioids, hypnotics,[link widoczny dla zalogowanych], anesthetics and other alcohol poisoning. Usage and dosage: 0.4mg ~ 0.8mr ~ ~, iH, or iV necessary, repeated every 20 ~ 30min. can 4mg +5% G.S1000ml,[link widoczny dla zalogowanych], to 0. 4mg / h infusion rate. severe poisoning,[link widoczny dla zalogowanych], particularly those with shock, available 30ug/kg intravenously, if necessary, repeat application after 1h the same dose. 5. benzene poisoning two class-specific antagonist flumazenil for the BZs agents, thus competing with the receptor antagonist N transcript of the second class of drugs. the first time, 0.3mg, intravenous injection, repeated administration, direct access to a total dose of 2mg. infusion can be controlled.
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