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Youth Lung Cancer


2,216870-6876 [16] l ~ ii beads and Practice of internal IM], first edition, Shanghai: People's Medical Publishing House. 2001:1593-1601 [17] Li Ru Yu, Qing-Quan Li,[link widoczny dla zalogowanych], youth clinical characteristics of lung cancer and misdiagnosis field, Practical Medicine, 200,420 (1) :61-62 [18] Li Zhenhua, Kong Ling Fei, Zhao Hongwen,[link widoczny dla zalogowanych], etc., young people lung cancer and lung cancer clinical and pathological features of the elderly compared fields of Clinical Oncology and Rehabilitation, 1997, (4) ~ 25-26 [19] Xiong Min, Hao a dragon 'is the first edition of lung pathology and clinical study the lf Beijing Carpenter Club M | 9 [20] Zhang Yan Bin, young people in 121 cases of lung cancer clinical and pathological 01, Guangdong Medicine, 2000,21 ( 669 [21] Fang Dekang, Wangliang Jun, Zhang Rugang and other young people the treatment of lung cancer resection Results Tian, ​​China Journal of Clinical Oncology, 1999,26 (6) :409-411 [22] Chen Enguo, should be the net, Zhao Chen,[link widoczny dla zalogowanych], young and old lung cancer compared Ⅱ】, cancer, 2003,233 (1) 69 - 70 [23] NugentWC, EdneyMT, HammemessPG, eta1. Non-smallcelllungcancerattheextremesofage: impactondi-agnosisandtreatmentlJ]. AnnThoracSurg ,[link widoczny dla zalogowanych],1997,63:193-197 [24] Shao Jie, Sun Fenglin, Wu Jun, etc., young people of lung cancer field, Journal of Practical Oncology, 1996,10 (4) 56.157 (Author: Fujian Longyan People Hospital 364000) related factors of the etiology of cleft lip and palate status Thestudyonthepossiblefactorsrelatedtothedevelopmentofcleftlipandpalate Xun Xue Zhen Zhang Rong Wang Rongyao Document code】 【A】 【Article ID 1606-6707 (2004) 10-0038-04 cleft lip and palate is the most common oral and maxillofacial A congenital malformation in newborns due to the incidence of race, ethnicity and region, about 1% o - 2 '% o. China is a country of high incidence of cleft lip and palate, cleft lip and palate after the incidence of neural tube defects in children up to 180000-210000 cases of fields. Seriously affect the quality of the population as cleft lip and palate, so the emphasis has always been an important academic research topics. The incidence of congenital cleft lip and palate causes and pathogenesis is not clear so far. 1.1 The mechanism of genetic factors 1: Most scholars believe that the genetic cleft lip and palate is through Gene for, the role of multi-gene threshold sector, chromosome abnormalities, abnormal plasma cells. 1.2 Heritability: Heritability is generally believed that for more than 60% means that genetic factors have a more important role; the other hand, said environmental factors have a more important role. W00 Caucasians in the United States to calculate heritability is 78%, Carter ~ Denmark and the United Kingdom calculated heritability of 76%. Hu Ning, China gave birth to groups of storks on the incidence of cleft lip and palate in Shanghai and the case of the family survey, total of 38 counted one, two, three genetic parents, respectively 79.17%, 79.77% and 77.54D6 ' average of 77.54%, the results with foreign close. Relative prevalence rate of 1.3 features: the genetic mutations of single genes of different genetic diseases, the prevalence of cleft lip and palate family members were studied by the group; by the relative level of impact; by the severity of patients; by gender of patients; by the family number of patients already in effect. 14 genetic risk: Many scholars believe that either parent suffer from cleft lip, cleft palate, its chance of abnormal offspring is 5%; and both parents have cleft lip, cleft palate, its probability is 15% genetic. First child, and as cleft lip, cleft palate children's parents, more children have never given birth to a deformed, there will be 25 times the normal chance of regeneration in cleft lip and palate patients; and two consecutive fetal cleft lip, cleft palate children's parents,[link widoczny dla zalogowanych], Comparison of unborn children cleft lip, cleft palate children, there will be 50 times the normal chance of regeneration in cleft lip and palate children. 15 parent's marital status: married cousin offspring a high incidence of cleft lip and palate in children of non-consanguineous marriage were the incidence of the disease. Inbreeding by both parties, the same can be obtained from the same ancestral gene, the same gene can be passed to offspring, and thus their offspring are homozygous for disease genes than random chance of marriage