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Long-term drug-eluting stent implantation combined clopidogrel and aspirin security analysis


. f7] GRINESCL, BONOWRO, CASEYDEJr, eta1. Preventionofprematurediscontinuationofdualanti-platelettherapyinpatientswithcoronaryarterystents. Circulation ,2007,115:813-818. [8] CAPRIESteeringCommittee. Arandomized, blinded, trialofclopi-dogrelversusaspirininpatientsatriskofischaemicevents (CAP-RIE). Lancet, 1996,348 (9038) :1329-1339. [9] Be ~ randME, RupprechtHJ, UrbanP, eta1. Double-blindstudyofthesafetyofelopidogrelwithandwithoutaloadingdoseincombina-tionwithaspirincomparedwithticlopidineincombina ·-tionwithas ·-pirinaftercoronarystenting: theclopidogrelaspirinstentinternationalco-operativestudy (CLASSICS). Circu-lation, 2000,102 (6): 62429. [10] He Liqun, MA Chang-sheng, Nie Shaoping, et al. Antiplatelet therapy after coronary intervention in the current status of drug therapy. Chinese Journal of Internal Medicine, 2006,16 (26):】 2,661,268. Sertraline and clomipramine in obsessive-compulsive disorder treatment control study Jin Gui-Hua Hanfeng Abstract Objective To compare sertraline and clomipramine in obsessive-compulsive disorder treatment efficacy and adverse reactions. Methods of sertraline and clomipramine in the treatment of obsessive-compulsive disorder, 30 cases for 8 weeks, the application Yale-Brown Obsessive Compulsive Disorder Scale (Y-BOCS), Hamilton Depression Rating Scale (HAMD) and Hamilton Anxiety Scale (HAMA) evaluated. Results of sertraline and clomipramine treatment Y. BOCS, HAMD, HAMA scores were significantly decreased, but sertraline rapid onset, fewer side effects. Conclusion Sertraline treatment of obsessive-compulsive disorder with clomipramine effect similar to light and less adverse reactions. Key words sertraline; clomipramine; obsessive-compulsive disorder sertraline literature reported a better effect on obsessive-compulsive disorder. To further investigate the efficacy and side effects,[link widoczny dla zalogowanych], to be controlled study with clomipramine. Are as follows. 1 Department of objects and object methods 1.1 June 2005 May 2006 l0 outpatient and inpatient hospital, in line with the Chinese Classification and Diagnostic Criteria of Mental Disorders 3rd Edition diagnostic criteria for obsessive-compulsive disorder; Yale-brown obsessive-compulsive disorder Scale (Y -BOCS) score ≥ 16 points, eliminate a serious organic disease, alcoholism or drug dependency, pregnancy and breast-feeding women. 60 Author: 152,300 mentally ill nursing home in Heilongjiang Province Helen (Gui-Hua Wang); Qiqihar City, the second neural psychiatric hospital (Korean phoenix gold) were randomly divided into the sertraline group and the clomipramine group. 3O sertraline group of patients, 16 males and 14 females, aged 16-47 years, mean (27.54-11.2) years, duration of 3 months for a 1O years, the average (4.8 ± 3.3 ),[link widoczny dla zalogowanych], the treatment Y. BOCS score was (28.5 ± 5.6) points. Clomipramine group 3O cases, male 17,[link widoczny dla zalogowanych], female l3,[link widoczny dla zalogowanych], aged 15-46 years, mean (26.44-10.9) years,[link widoczny dla zalogowanych], duration of 4 months to 11 years, the average (4.2 ± 3. 2) years before treatment Y-BOCS score was (29.64-5.7) points. The above two groups were not significantly different (P> 0.05). 1.2 The method has been 1 week drug washout. Sertraline dose 50-150mg / d, clomipramine dose from 50ms / d started, gradually increase the amount added to the 100-300ms / d, treatment was 8 weeks. Efficacy of using Y-BOCS, Hamilton Depression Rating Scale (HAMD) Han close