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ed hardy swimwear 尼卡地&#

 
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PostPosted: Sun 11:17, 13 Mar 2011    Post subject: ed hardy swimwear 尼卡地&#

尼卡地平对心脏瓣膜置换术病人肺缺血/再灌注损伤的保护作用
给予尼卡地平,可有效防止腔静脉开放后5minPMN在肺内的滞留,[link widoczny dla zalogowanych],这种作用可能是通过尼卡地平的抗缺血作用,防止了由于缺血而导致的肺血管内皮细胞表面粘附分子的表达以及抑制XD向XOD的转化。从本研究的结果可看出,[link widoczny dla zalogowanych],CPB前预防性给予0.02mg·kg的尼卡地平,不论肺循环指标MPAP和PVRI,还是肺气体交换功能指标PaO/FiO、Pf.。)O、Qs/Qt和肺顺应性均得到有效改善,且明显优于对照组病人。说明在CPB前,给予小剂量尼卡地平可以作为预防肺I/R性肺损伤的有效措施。总之,[link widoczny dla zalogowanych],CPB下肺I/R损伤可导致病人肺功能的严重损害,[link widoczny dla zalogowanych],炎性反应介导的中性粒细胞激活且在肺内驻留可能是造成肺功能损害的机制,[link widoczny dla zalogowanych];CPB前给予小剂量尼卡地平0.02mg·kg一,可以预防由CPB导致的肺功能损害,其作用机制可能与其抗肺缺血效应介导的抗炎作用有关。
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