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Cholerny Spammer
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Posted: Sun 20:37, 20 Mar 2011 Post subject: ed hardy bikini Human liver insulin-like growth fa |
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Human liver insulin-like growth factor Ⅱ gene P2,[link widoczny dla zalogowanych], P4 cloning and sequence analysis
Or less have generated mutations,[link widoczny dla zalogowanych], deletions and other changes may be related to abnormal expression of IGF 1I a mechanism of transcriptional regulation of the expression of irrelevant or not the main reason for their excess . However, this study due to limited time and conditions , fewer cases of liver cancer specimens , received only a preliminary result, not the final conclusion. At present we are still to collect liver samples for liver cancer in a 1I IGF promoter base sequence , structure and function for a more comprehensive study . 1I IGF gene expression is regulated by a number of factors,[link widoczny dla zalogowanych], including genomic imprinting, regulation of transcription and translation level ,[link widoczny dla zalogowanych], among which is the regulation of key transcription level . In the course of the development of liver cancer , P2 ~ P4 P1 re- activation and inactivation of participation may be the result of a variety of mechanisms . Prior to P1,[link widoczny dla zalogowanych], P3 and the study P2, P4 promoter cloned for further study on liver cancer in a 1I IGF levels in promoter methylation and its transcriptional activity , analysis of promoter activity of different transcription regulatory elements to Clear P2 ~ P4 and P1 and then activate the mechanism of inactivation of the foundation .
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