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Posted: Tue 5:59, 01 Mar 2011 Post subject: ecco shoes outlet DNA疫苗及&am |
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DNA疫苗及其优化策略
forconstructingplasmidvectors.Gene,2001;272:149~15631MikkelsenTR。ChapmanB,DinN,eta1.Trans—genieRes,1992;1:164~16932DemlL,BojakA,[link widoczny dla zalogowanych]。SteckS,eta1.JVirol,2001l75:10991~1001.66033KotsopoulouE,KimVN,KingsmanAJ。eta1.JVirol,2000l74:4839~4852.34VinnerL,NielsenHV,BryderK,eta1.Vaccine.国外医学病毒学分册1999;17:2166~617535ZurMegedeJ·ChenMC,DoeB·eta1.JVirol·2000;74:2628~263536UchijimaM,YoshidaA,NagataT,[link widoczny dla zalogowanych],KoideY.JIm—munol,1998;161:5594~559937NarumDL,KumarS,RogersWO,eta1.InfectIm—mun,2001;69:7250~725338BolmstedtA。HinkulaJ。RowcliffeE。eta1.Vac—cine,2001Novl2l20(3~4):397~40539ShroffKE。SmithLR,BaineY,eta1.Pharmaceu—ticalScience8LTechnologyToday,1999~Vo12(5):205~21240SinJI,[link widoczny dla zalogowanych],KimJ,ChattergoonM,eta1.DevBiol(Base1),2000l104:187~19841WilliamsNA,HirstTR。NasharT0.IMMUN0L一0GYT0DAY,1999lVo120(2):9542SinghM·VajdyM,GardnerJ,eta1.Vaccine,2001Nov12;20(3~4):594~60243ShroffKE,[link widoczny dla zalogowanych]。SmithLR,BaineY,eta1.Pharmaceu—ticalScience8LTechnologyToday。1999~Vo12(5):205~21244SwainWE,HeydenburgFullerD。eta1.DevBiol(Base1),2000I104:115~11945GieseM,BahrU,JakobNJ。eta1.VirusGenes,20020et;25(2):159~16746DeRoseR,TennentJ,McWatersP,eta1.VetIm—munolImmunopathol,2002VovI90(1~2):55~6347HoffmanSL,DoolanDL.DevBiol(Base1),2000l】04:12】~】32慢病毒载体与基因治疗第一军医大学肿瘤研究所(广州510515)杨玉芳综述丁彦青审校[摘要]载体是供插入目的基因并将其导入宿主细胞内表达或复制的运载工具。常用的有SV.。衍生载体、逆转录病毒载体、腺病毒载体、腺病毒相关病毒载体、细小病毒载体、疱疹病毒载体、痘苗病毒载体等。近几年来。慢病毒载体受到高度重视,慢病毒载体来源于人类免疫缺陷病毒HIV一1、HIV一2、SIV,[link widoczny dla zalogowanych],具有转染和非的T细胞、树枝状细胞、造血干细胞及巨噬细胞Ⅲ,基因疗法是一种新方法。Hawley等的文章中指出。由于慢病毒载体可作用于细胞周期的G0/G1期·成为遗传性疾病治疗的有效手段。基因治疗的最初目的是传送特殊的基因至预定的
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