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Diagnosis and treatment of acute fatty liver of pregnancy


Fever, the first 3 days of liver coma, acute pancreatitis. But after an active rescue 4 to 8 days, through the very period. Condition will gradually improve. AFLP has not clarified the cause of the current, but the hormonal changes of pregnancy, barriers to protein synthesis, lipid metabolism disorder is a certain relationship. Termination of pregnancy, the body may be terminated in some areas is conducive to the rescue of pregnant women, so we think that timely treatment of AFLP termination of pregnancy is the key measure. 2.3 Prevention of postpartum shock is to prevent multiple organ dysfunction syndrome (MODS) after an important step in cesarean section, patients often have low blood pressure. Little or no urine, acute circulatory failure. May be due to many factors. Hypoproteinemia, intrapartum hemorrhage, ascites, abdominal pressure caused by a sudden fall in the effective hypovolemia; infection of toxin absorbed, surgical trauma, the release of vasoactive substances in the body, causing a strong contraction of capillaries, resulting in circulation of Zhenjiang Medical College JOURNALOFZI -IENJIANCt 't ~ DICALCOIJ. F ~ E2000, 10 (3) hypoperfusion, so that tissue ischemia and hypoxia. Shock increased liver and kidney damage, can lead to cerebral edema, hepatic coma, acute azotemia and so on. Sustained severe low blood volume status,[link widoczny dla zalogowanych], can microcirculation stasis, tissue hypoxia, accumulation of metabolic acid production, capillary wall damage, in addition to bleeding, clotting factors are consumed, prone to DIC. Shock and multiple organ dysfunction is a sign of the start-factor integrated units, to restore effective blood volume, improve microcirculation, correcting water, power bait quality, acid-base balance of blood and oxygen supply is to protect the cells of liver and kidney failure prevention and treatment of postpartum AFLP, DIc an important step. When liver damage is very important to rehydration, rehydration too easily lead to ascites, liver and kidney function of too little fluid, affecting microcirculation and tissue cells of the blood and oxygen supply. We believe that within 3-5 days after operation, the liquid should not be too many restrictions, requirements for the normal physiological loss of 80% plus an additional amount of supply is appropriate. 5g of sodium chloride control the following day, and use of mannitol, furosemide, so that patients in a mild state of dehydration, can reduce the formation of ascites, and prevent hepatic encephalopathy. Lose fresh plasma, albumin, not only can increase plasma colloid osmotic pressure, to maintain effective circulation, and can add coagulation factors, complement, opsonin, to correct bleeding tendency, increased disease resistance, to correct hypoproteinemia, excretion of toxic products, enabling regeneration.