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PostPosted: Wed 4:12, 02 Mar 2011    Post subject: asics tiger shoes 一株鹅H5N1&a

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一株鹅H5N1亚型流感病毒基因特性的分析
18—225lRKGelfandDHSlallels.Ha】P川directedenzymaticamplificationofDNAwilh8thermos*ableDNApolymer~seS~ienee,1988.239:4874926WoodGW.Mcc~uleyJW.BⅡLrudd_¨JB,HalDeducedaminoacidsequen~atthehemagglulinincleavagesjteofH5N1avianinfluenzav…hDma力lHl『breakinturkeysinNorfalkEnglandArchVirol、1994.134:185—1947VogelG.~quenceofferselu~s佃deadlyfluScien~,1997,279j3248GarciaM.Crawf~rdJM,LatimerJW.alHeterogeneityinthehaemagglufinlngeneandemergenceofthehighlypathngeniephenotypeamong…mH5N2a~4aninflue~virusesfromMexicoJC-enVirol,1996.77:149315039Kaw~kaYNaeveCW.WeterRGIsvirulenceofH5N2lnfluenzaⅦruseslnchicke【lsassociatedw】th】o路一bobydrstefr0mthehenmgglmirtin?Vi~[ogy.1984.139:30331610AirGM.BlokIBlockddetionsintheneurarmmdaseg…f0rsameinflueraaAnl鼬softheN1subtypeVirology.1982,l18:2292341lSngiumA.UedaMNeurovirulenceofinfluenza…inmice1NeurovirulentvirusstrainVirofogy.1980,101:440—44912tLA.NayakDP.Completenuel~tidesequenceoftheneuraminid~geneofksmmninflue~a/WSN/33】Vi—rol,1982.41(2):730—734干扰素抗病毒的范围很广,对RNA和DNA病毒都有明显的抑制作用,[link widoczny dla zalogowanych],但对DNA病毒作用稍差。病毒唑亦具有广谱抗病毒作用,对RNA及DNA病毒亦有明显抑制作用,[link widoczny dla zalogowanych],特别是对RNA病毒作用显著。腮腺炎病毒属副粘渡病毒类,[link widoczny dla zalogowanych],系RNA病毒。因此,干扰素与病毒唑对其均有较强抑制作用。但二者抗病毒的作用机理不同。本文结果显示,在发热、腮腺肿痛、头痛呕吐及脑膜刺激征等控制,血清淀粉酶、脑脊渡、脑电囤等恢复正常时问及平均住院时问等方面,干扰素(IFN一02b)略优于病毒唑组.这可能与干扰素(IFN一02b)不仅具有抗病毒作用,同时还具有明显的免疫调节活性及增强巨琏细胞的吞噬功能的作用,有益于机体康复有关,但经统计学处理并无显著差异(均为P>0.05).表明二药对腮腺炎病毒的抑制作用相似而联台用药后,在以上诸方面的疗效均优于二药单用组(P<0,05~P<0.O1),可能是二药对腮腺炎病毒产生抑制作用的途经不同,联台用药后产生了协同抗病毒作用,[link widoczny dla zalogowanych],因而对腮腺炎病毒抑制作用较强的结果。干扰素(IFN一02b)与病毒唑对流行性腮腺炎及其并发症脑膜脑炎均有良好疗效,二药联台应用可产生协同抗病毒作用.显著提高疗效.且用药时间短,无明显副作用,值得推广应用。
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