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火把花根片

 
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lin91957
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PostPosted: Mon 15:09, 28 Feb 2011    Post subject: 火把花根片

火把花根片治疗IgA肾病60例临床观察
ineseTraditionalandHerbalDrugs2001年第32卷第9期表2火把花根治疗组疗效与igAN病理类型的关系(例)组别倒数显效好转无效总有效率()止把花根组60182715750雷公藤组348179735病的中草药制剂,火把花根片有较好的抗炎作用,能抑制毛细血管通透性,减少渗出,抑制增生,具有较强的免疫抑制剂的效应。IgA肾病的病理特征是以肾小球系膜区有IgA或以IgA为主的免疫复合物沉积及局灶节段或弥漫性系膜增生为特征表现]。因此,我们选用火把花根片治疗IgAN取得较好疗效,总有效率为75.0,与雷公藤多苷片(总有效率为73.5)比较未见显著差异(尸>0.05)。本研究还发现,火把花根片疗效与IgAN的临床和病理类型有关,从临床类型看,无症状性尿异常疗效最好,而肾炎综合征疗效最差;从病理类型看,I~Ⅱ级疗效优于Ⅲ~IV级,病理损害越重,疗效越差火把花根片治疗的6O例疗程中仅2例出现轻度白细胞减少,而雷公藤组疗程中发现白细胞减少3例,肝功能异常(谷丙转氨酶升高)2例,停经3例,脱发1例。表明与雷公藤多苷片相比,火把花根片有“低毒”的优势。火把花根片是治疗IgA肾病的一种高效低毒的中草药制剂,能否取代疗效不可靠且副作用大的糖皮质激素、细胞毒类药物,更广泛地治疗各种肾小球肾炎,需作进一步的临床观察
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